The Effect of Local Peripheral Resistance on Systemic Arterial Pressure

Abstract

The immediate mechanical effect of changes in peripheral resistance of a local flow region on systemic arterial pressure was theoretically studied. Assuming proportionality between pressure and flow and constancy of cardiac output, the following theoretical relationship was derived : b=ad/(1+a-ad), where b=rate of change in arterial pressure, a=rate of change in peripheral resistance of the particular region and d=initial ratio of the local flow to cardiac output. Using this formula, effects of superior mesen-teric flow fluctuation and rhythmic splenic contraction on arterial pressure were analyzed.