Modeling of Left Ventricular Motion and Hemodynamic Analysis Based on CT Tomography

Abstract

Based on Computed Tomography (CT) tomography images of the human heart, a 3D reconstruction and wall optimization of the heart was performed by using Mimics to model the motion of the left ventricular overflow wall. The non-Newtonian blood flow in the left ventricle was numerically simulated using the dynamic mesh technique based on User Defined Functions (UDF) programming of the left ventricular wall motion. When the left ventricle is diastolic, the internal pressure gradually increases, the blood flow structure approximates the physiological blood flow pattern, the rate at the mitral orifice first increases and then decreases, and a local high stress zone appears. When the left ventricle is systolic, the pressure gradient is significant, the internal pressure decreases and the rate at the aortic valve orifice shows a pattern of increasing and then decreasing. The dynamic simulation of left ventricular blood flow provides a feasible technical solution for the fluid dynamics analysis of cardiac physiological and pathological processes.