Adherence support intervention for patients on ixazomib therapy using counseling and a “patient medication notebook”

Abstract

We developed an adherence support intervention using both counseling and a “patient medication notebook (Note),” which was provided by a certified nurse in cancer chemotherapy nursing (CN) and pharmacists for patients with multiple myeloma on ixazomib therapy. In the hospital, the CN provided counseling sessions to not only educate patients but also define objectives associated with their daily life. After discharge, pharmacies that share data about each patient and the customized objective using the “Note” supported adherence continuously. Nine patients suggested the intervention, including the median counseling sessions of 5 (3–7). By the second counseling session, we set a tailored goal for each patient. This intervention contributed to a grasp of adverse events (AEs), resulting in appropriate management. In patients who experienced AEs, their goal and mental support validation for anxiety by the CN resulted in continued motivation for treatment ixazomib. Furthermore, adherence support intervention could be feasible and effective for ixazomib-treated patients.