Histoculture Drug Response Assay for Identifying Effective Anticancer Agents for Oral Squamous Cell Carcinoma: Report of Two Cases

Yasunori Ariyoshi; Masashi Shimahara; Nobuhiko Tanigawa; Motomu Tsuji

doi:10.5466/ijoms.2.44

Case Reports

Histoculture Drug Response Assay for Identifying Effective Anticancer Agents for Oral Squamous Cell Carcinoma: Report of Two Cases

Yasunori Ariyoshi, Masashi Shimahara, Nobuhiko Tanigawa, Motomu Tsuji

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Keywords: histoculture drug response assay, MTT assay, mouth neoplasm, squamous cell carcinoma

JOURNAL FREE ACCESS

2004 Volume 2 Issue 1 Pages 44-49

DOI https://doi.org/10.5466/ijoms.2.44

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Abstract

Two cases of unresectable squamous cell carcinoma of the oral cavity were treated with combination chemotherapy using drugs determined to be effective in histoculture drug response assay with MTT end point. Both cases showed good response to the chemotherapy. The present results suggest that chemosensitivity testing facilitates individualization of chemotherapy.

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