International Journal of the Society of Materials Engineering for Resources
Online ISSN : 1884-6629
Print ISSN : 1347-9725
ISSN-L : 1347-9725
Originals
Discrimination of Double Strand DNA Based on Doubly Pyrene Modified Cyclodextrins
Shou NEMOTOToru SUZUKIShun SAITOUNatsumi ISHIZUKASotarou KOBAYASHIFumio HAMADA
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2013 Volume 19 Issue 1_2 Pages 1-10

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Abstract
In a series of study on development of discriminating agents for single and double strand DNA (ss-DNA and ds-DNA, respectively) based on di-pyrene modified cyclodexytrins (CyDs), compound 1 which was modified at A, D of glycopyranose of α-CyD, compound 2 which was modified at A, B of glycopyranose of β-CyD, and compound 3 which was modified at A, D of glycopyranose of γ-CyD, when consisting glucopyranose units of α-, β- and γ-CyDs are lettered from A to F, from A to G and from A to H, respectively, are able to discriminate with ss- and ds-DNA. Discriminating system is realized as behavior of their fluorescent emission intensity in addition of single and double strand DNA
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© 2012 The Society of Materials Engineering for Resources of Japan
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