International Journal of Surgical Wound Care
Online ISSN : 2435-2128
Case Reports
Combination of Intravenous and Intralesional Sodium Thiosulfate for the Treatment of Calciphylaxis
Kazuki UenoYoshitaka WadaYoshifumi IwahashiShinichi MurataShinichi Asamura
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2020 Volume 1 Issue 3 Pages 120-124

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Abstract

Calciphylaxis is a rare and life-threatening disorder characterized by painful skin ulceration. Treatment is not yet standardized; however, a case of calciphylaxis successfully treated by intravenous sodium thiosulfate was reported in 20041). Since then, several reports have supported the use of sodium thiosulfate in the treatment of calciphylaxis. However, intravenous administration of sodium thiosulfate may be limited owing to its systemic side effects. We report the successful treatment of a female patient with intractable right-leg calciphylaxis who was administered both intravenous and intralesional sodium thiosulfate combination therapy without side effects.

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© Japan Society for Surgical Wound Care 2020
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