Two Refractory Cases of Ulcer with Achilles Tendon Exposure Treated with bFGF Inserted into Pelnac-Gplus^® Following Negative Pressure Wound Therapy

Abstract

Skin leg ulcers with Achilles tendon exposure are refractory to conventional treatments. These ulcers are caused by conditions such as diabetes, venous insufficiency, arterial sclerosis, and collagen disease. We encountered two cases of refractory skin leg ulcers with Achilles tendon exposure. These patients have venous insufficiency and take a long time to cure at other hospitals. We used an artificial dermis, namely Pelnac-Gplus^®, combined with a basic fibroblast growth factor (bFGF) formulation to treat these ulcers following negative pressure wound therapy for a month. A good result was obtained two weeks after the skin graft was performed. One year postoperatively, the lesion was followed a good course, and the ulcers did not recur.