International Journal of Surgical Wound Care
Online ISSN : 2435-2128
Original Article
Surgical Management of Osteoradionecrosis: Perioperative Problems Encountered during 19 Years of Experience Managing Complicated Cases
Kosuke MoriokaAmi HigashiyamaAiri TazakiSawa IkarimotoTakashi SugawaraKota HagiwaraKoji IharaHiroyuki Sakurai
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2023 Volume 4 Issue 3 Pages 81-91

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Abstract

Background: Osteoradionecrosis significantly reduces quality of life. In this study, we reviewed our experience of surgically managing complicated cases of osteonecrosis and discussed the perioperative problems encountered.
Methods: We retrospectively evaluated 15 patients with osteoradionecrosis of the craniofacial or trunk skeleton who underwent flap reconstruction surgery at our institution between January 2002 and December 2021. In all cases, the irradiated tissues were excised, followed by coverage with well-vascularized tissue. Surgical methods and postoperative complications were evaluated as outcomes.
Results: The 15 patients included six men and nine women, with a mean age of 67.8 ± 17.0 years (range 20–83 years). The affected bone was the skull in one case, mandible in five cases, clavicle in one case, ribs in five cases, sacrum in two cases, and pubic bone in one case. In seven cases, a postoperative fistula formed in the craniofacial or pelvic region. The fistulas in the craniofacial region were closed by the removal of the infected plate or excision of the sequestrum.
Conclusions: Surgical treatment of osteoradionecrosis should include excision of the irradiated tissues followed by coverage with well-vascularized tissue. Well-vascularized transplanted tissues can be effective for wound healing in complicated cases.

A 75-year-old man with osteoradionecrosis of the skull (case 1). Fullsize Image
(a) Preoperative photograph showing necrotic parietal bone. (b) Sagittal preoperative computed tomography (CT) showing epidural abscess and brain edema. (c) Sagittal T1-weighted image showing an area of low intensity in the parietal bone. (d) Fresh bleeding after wide excision of the devitalized tissue. (e) The latissimus dorsi musculocutaneous flap and serratus anterior muscle with the eighth and ninth ribs designed on the right chest wall. (f) Ribs fixed with absorbable stitches across the parietal bone defect and the serratus anterior muscle covering the central portion of the defect. (g) CT image taken 14 months after surgery with a red arrow denoting the progression of necrosis of the marginal bone. (h) Photograph taken 16 months after surgery showing closure of the fistula.
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© Japan Society for Surgical Wound Care 2023
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