Abstract
The DPC (Diagnosis Procedure Combination) database is a national inpatient database in Japan, which includes approximately 7 million inpatients per year from more than 1000 hospitals. DPC data include administrative claims data and some clinical data. Recently, studies using the DPC database are increasing. In this report, we explain three of the DPC studies about (i) outcomes of argatroban treatment in patients with atherothrombotic stroke, (ii) comparison of short-term mortality and morbidity between parenteral and enteral nutrition for adults without cancer, and (iii) validation of the prognostic burn index. Also, several ongoing and future issues on large healthcare databases including the DPC database are discussed.