Salvage Endoscopic Submucosal Dissection for Local Recurrence of Superficial Esophageal Squamous Cell Cancer after Photodynamic Therapy

Akira Kanamori; Kenichi Goda; Tetsuya Nakamura; Hidetsugu Yamagishi; Atsuko Ohwada; Keiichiro Abe; Tsunehiro Suzuki; Masayuki Kondo; Takanao Tanaka; Akira Yamamiya; Yoichi Takimoto; Koki Hoshi; Takahiro Arisaka; Takeshi Sugaya; Keiichi Tominaga; Yuichi Majima; Makoto Iijima; Atsushi Irisawa

doi:10.2169/internalmedicine.8573-21

CASE REPORTS

Salvage Endoscopic Submucosal Dissection for Local Recurrence of Superficial Esophageal Squamous Cell Cancer after Photodynamic Therapy

Akira Kanamori, Kenichi Goda, Tetsuya Nakamura, Hidetsugu Yamagishi, Atsuko Ohwada, Keiichiro Abe, Tsunehiro Suzuki, Masayuki Kondo, Takanao Tanaka, Akira Yamamiya, Yoichi Takimoto, Koki Hoshi, Takahiro Arisaka, Takeshi Sugaya, Keiichi Tominaga, Yuichi Majima, Makoto Iijima, Atsushi Irisawa

Author information

Akira Kanamori
Department of Gastroenterology, Dokkyo Medical University, Japan
Kenichi Goda
Department of Gastroenterology, Dokkyo Medical University, Japan
Tetsuya Nakamura
Department of Gastroenterology, Dokkyo Medical University, Japan
Hidetsugu Yamagishi
Institutional Research Center, Dokkyo Medical University, Japan
Atsuko Ohwada
Department of Diagnostic Pathology, Dokkyo Medical University, Japan
Keiichiro Abe
Department of Gastroenterology, Dokkyo Medical University, Japan
Tsunehiro Suzuki
Department of Gastroenterology, Dokkyo Medical University, Japan
Masayuki Kondo
Department of Gastroenterology, Dokkyo Medical University, Japan
Takanao Tanaka
Department of Gastroenterology, Dokkyo Medical University, Japan
Akira Yamamiya
Department of Gastroenterology, Dokkyo Medical University, Japan
Yoichi Takimoto
Department of Gastroenterology, Dokkyo Medical University, Japan
Koki Hoshi
Department of Gastroenterology, Dokkyo Medical University, Japan
Takahiro Arisaka
Department of Gastroenterology, Dokkyo Medical University, Japan
Takeshi Sugaya
Department of Gastroenterology, Dokkyo Medical University, Japan
Keiichi Tominaga
Department of Gastroenterology, Dokkyo Medical University, Japan
Yuichi Majima
Department of Gastroenterology, Dokkyo Medical University, Japan
Makoto Iijima
Department of Gastroenterology, Dokkyo Medical University, Japan
Atsushi Irisawa
Department of Gastroenterology, Dokkyo Medical University, Japan

Keywords: chemoradiation therapy, endoscopic submucosal dissection, esophageal squamous cell cancer, photodynamic therapy, salvage therapy

JOURNAL OPEN ACCESS

2022 Volume 61 Issue 14 Pages 2149-2153

DOI https://doi.org/10.2169/internalmedicine.8573-21

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Abstract

Photodynamic therapy is useful as organ-preservation salvage therapy for residual recurrence of esophageal squamous cell carcinoma after chemoradiation therapy. However, the high residual recurrence rate of photodynamic therapy poses a problem. We herein report a patient who underwent photodynamic therapy for recurrence of superficial esophageal squamous cell carcinoma after chemoradiation therapy. The patient later exhibited another episode of recurrence of superficial esophageal squamous cell carcinoma, and R0 curative resection was obtained with endoscopic submucosal dissection. This suggests that endoscopic submucosal dissection may be an effective treatment option that can achieve R0 resection even for residual superficial cancer after salvage photodynamic therapy.

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