Malignant Lymphoma Involving the Penis Following Malignant Pleural Mesothelioma

Kazuhiko TAKABE; Yoshikazu TSUKADA; Takashi SHIMIZU; Jun TAKAGIWA; Minoru HIRAYAMA; Morito NAKAYAMA; Hirotaro MIURA; Hisamasa AKABANE; Shigemitsu TAKAYAMA; Shinsuke AIDA; Yuji KIMURA

doi:10.2169/internalmedicine.36.712

Kazuhiko TAKABE, Yoshikazu TSUKADA, Takashi SHIMIZU, Jun TAKAGIWA, Minoru HIRAYAMA, Morito NAKAYAMA, Hirotaro MIURA, Hisamasa AKABANE, Shigemitsu TAKAYAMA, Shinsuke AIDA, Yuji KIMURA

Author information

Kazuhiko TAKABE
The Department of Internal Medicine and, Yokosuka Kyosai Hospital
Yoshikazu TSUKADA
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Takashi SHIMIZU
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Jun TAKAGIWA
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Minoru HIRAYAMA
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Morito NAKAYAMA
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Hirotaro MIURA
The Department of Internal Medicine, Yokosuka Kyosai Hospital
Hisamasa AKABANE
The Department of Pathological Anatomy Service, Yokosuka Kyosai Hospital
Shigemitsu TAKAYAMA
Kan Kogyo Health Care Center Clinic
Shinsuke AIDA
The Department of Laboratory Medicine, National Defense Medical College
Yuji KIMURA
The Department of Pathology, Patan Hospital

Keywords: B-cell malignancy, multiple myeloma, asbestos exposure

JOURNAL FREE ACCESS

1997 Volume 36 Issue 10 Pages 712-715

DOI https://doi.org/10.2169/internalmedicine.36.712

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Abstract

A 74-year-old man who had been diagnosed with malignant mesothelioma developed malignant lymphoma of B-cell origin involving the penis. He had a history of occupational exposure to asbestos as a construction worker. The association of malignant mesothelioma with lymphoma is rare, and the possibility of asbestos exposure as a common etiology is discussed. The intense stimulation of B lymphocytes and decreased T lymphocyte activity in asbestos-exposed populations may result in development of B-cell malignancies. Though the relationship between asbestos exposure and malignant mesothelioma is firmly established, the relationship between asbestos exposure and lymphoma remains to be investigated.
(Internal Medicine 36: 712-715, 1997)

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