Recently, manufacturing companies have been moving into product-based service businesses in addition to providing the products themselves. However, it is not easy for engineers in manufacturing companies to create new service businesses because their skills, mental models, design processes, and organization are optimized for product design and not for service design. In order to design product-based services more effectively and efficiently, systematic design methodologies suitable for the service businesses are necessary. Based on the case analysis of more than 40 Japan-US product-based services, this paper introduces a product-based service design methodology called DFACE-SI. DFACE-SI consists of five steps from service concept generation to service business plan description. Characteristic features of DFACE-SI include visualization tools to facilitate stakeholders' recognition of new opportunities and difficulties of the target product-based service. Opportunities and difficulties are recognized using the customer contact expansion model and the failure mode checklist, respectively, which are extracted from the service case analysis. We apply DFACE-SI to a pilot project and illustrate its effectiveness.