Intractable & Rare Diseases Research
Online ISSN : 2186-361X
Print ISSN : 2186-3644
ISSN-L : 2186-3644
Reviews
Dry age-related macular degeneration: A currently unmet clinical need
Jean-François GirmensJosé-Alain SahelKatia Marazova
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JOURNAL FREE ACCESS

2012 Volume 1 Issue 3 Pages 103-114

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Abstract

Age-related macular degeneration (AMD) is a leading cause of severe visual impairment and disability in older people worldwide. Although considerable advances in the management of the neovascular form of AMD have been made in the last decade, no therapy is yet available for the advanced dry form of AMD (geographic atrophy). This review focuses on current trends in the development of new therapies targeting specific pathophysiological pathways of dry AMD. Increased understanding of the complex mechanisms that underlie dry AMD will help to address this largely unmet clinical need.

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© 2012 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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