Intractable & Rare Diseases Research
Case Reports
Anaplastic myxopapillary ependymoma in an infant: Case report and literature review
Darshan TrivediZhenggang Xiong
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Volume 6 (2017) Issue 2 Pages 128-131

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Abstract

A 7-month-old boy presented with gastrointestinal disturbance, mild neurologic deficit of the left lower extremity and levo-scoliosis of the thoracic spine. Magnetic resonance imaging demonstrated a large intramedullary lesion involving the thoracic spine, from level T1 to T11. Histologic analysis showed a glial tumor with fibrillary processes arranged in radial pattern around mucoid fibrovascular cores with a high proliferative index (focally up to 80%) and prominent vascular endothelial hyperplasia. These findings were consistent with an anaplastic myxopapillary ependymoma. Subtotal resection was performed via a T3-T10 laminoplasty. A ventricular shunt was placed, and the patient subsequently received chemoradiation therapy. To date, this is the second case of a myxopapillary ependymoma with high-grade anaplastic features and the first case in an infant reported in the literature.

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© 2017 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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