Abstract
1. In 72 cases of hyperthyroidismus rate of thyroid uptake and basal metabolic rate were determined. In 63 cases, higher values became normal by the first or the second treatment with I131.
2. Before the treatment, the averaged value of basal metabolic rate was plus 38.3% (plus 9% to 80%). After the treatment, it decreased to plus 1.4% (plus 15% to minus 12%). The averaged value of thyroid uptake of I131 was 59% (30% to 90%) before the treatment. It decreased to 25% (7% to 40%) after the treatment. 3. In some cases, when the dose of I131 was insufficient, thyroid uptake and basal metabolic rate increased slightly.
In consideration of the size of thyroid gland and the basal metabolic rate in each case, the dose of 1131 should be carefully determined.