Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Studies on the Drug Resistance of Tubercle Bacilli Cultivated from the Patients with Kidney Tuberculosis and the Clinical Progress
Shozo IWATAToshio TSUCHIYA
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1964 Volume 18 Issue 11 Pages 821-825

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Abstract
We cultivated the urine from 26 patients who had kidney tuberculosis and had visited to our clinic recently, in whom tubercle bacilli were positive in the 13 cases. We found that SM resistant bacilli were 30.7 per-cent, INH 23.1 per-cent and non-resistant bacilli on PAS. Generally SM resistance became higher in proportion to overall doses of SM administered, but as to INH no distinct relation was found between the resistance and the medicine administered. About the clinical progress, although it was depend on the combined therapy of SM, INH and PAS, the patients of non-resistant to these medicines had been doing well as well as the patients of resistant to these medicine and received surgical operation for unilateral kidney tuberculosis.
But on the cases of bilateral kidney tuberculosis or the one which exstirpated already one side due to kidney tuberculosis and was resistant to these medicine should be considered to change the medicine adequately. For this purpose the resistant test must be performed at the first medical examination and during the course as well. On the case that tubercle bacilli were not cultivated the change of the medicine should be carefully considered by the clinical progress.
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© Japanese Society of National Medical Services
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