Abstract
By clinical investigations about 4, 456 cases of primary cancers of our hospital from May, 1962 until December, 1964, the incidence of skeletal metastasis was revealed in 225 patients, at the rate of 5 per cent.
The clinical evidences were usually supported by roentgenological surveys, but in 62 cases the metastatic bone lesions were discovered only at post mortem table.
The most common sources of bone metastasis in our series were indicated to be in the kidney (35.3%) and the prostate (32.0%).
Vertebral column and pelvis were the most common sites of metastasis, and metastatic deposits were sometimes osteosclerotic, most frequently in prostatic cancers (87.5%).
As for the treatment of extensive skeletal metastasis, especially of the hormone-dependent cancers, the endocrine therapy including the bilateral adrenalectomy with castration or oophorectomy have been proved to be most effective for the palliation of their conditions and the improvement of their bone lesions.
