Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Intraarterial Infusion of Anticancer Agents in Hepatic Tumor and Application of Hepatography
-By Oil Salable Radiopaque, Lipiodolultrafluid
Seijira ISHIKAWAMasco FUJIMORI
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1967 Volume 21 Issue 1 Pages 42-47

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Abstract
It is very difficult to determine the effect of anticancer agents infused into hepatic artery in malignant hepatic tumors, of either primary or secondary.
We accepted hepatogram taken by water soluble radiopaque material (Urographin) as a indicator by fluctuation of the size of tumor, to find out the effect of intraarterial infusion. Hepatogram taken 10-12 seconds after portal infusion of radiopaque material recongnized the difference as much as 1.0 cm in diameter. To see the fluctuation of tumor, portal hepatogram is much excellent than the one through hepatic artery.
Hepatogram by oil soluble radiopaque material (Lipiodol ultrafluid) showed portal branches within liver by 24 hours after procedure, and thereafter showed sinusoid endothelial cells, that is, shadow of liver itself. Lipiodol ultrafluid remains as long as one month, and changing size of tumor could be pursued for long time.
The above mentioned method is simple and excellent to observe the effect of intrahepatic arterial infusion against hepatic tumors.
This method has little effect on liver function and can be taken in ordinary radiography.
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© Japanese Society of National Medical Services
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