Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
The Cholesterol-Lowering Agents, Part 6 Cholesterol-Lowering Effects of Pyridoxine HCl.
Akira YAMAZAKIYasuki HATTORI
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1967 Volume 21 Issue 3 Pages 329-334

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Abstract
There are some reports that recognized existence of the relationship between Vitamin. B6 and arteriosclerosis, Also Schroeder and others reported that Vitamin B6 treatment has a cholesterol-lowering power. It is not always said that hypercholesterolemia induced to arteriosclerosis, but we can not denied that there are some relationship between hypercboiesterolemia and arteriosclerosis.
Thus we studied with the cholesterol-lowering effects of pyridoxine HCL (80-150 mg/day orally)
Our results are as follow:
1) In this case cholesterol-lowering effects were seen in about 20-40% and levels of serum cholesterol were reduced to about 80-90% of the former levels. But when the former levels were beyond 300mg/dl, these effects were less.
2) In the cases of arteriosclerosis and obesity some effects (in about 40% cases). were obtained, but in nephrosis, diabetes mellitus, fatty liver and so on no effects were seen.
3) In the cases of combined therapy with pyridoxine and jodlecithin cholestrollowering effects were larger than the effects of only Vitamin B6.
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© Japanese Society of National Medical Services
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