Abstract
During the past 7 years 42 out of 2, 603 (1894 males, 709 females) hospitarized pulmonary tuberculous patients had diabetes mellitus. There was no differece in sex distinction. The yearly percentage of this complication was about 1.5% and did not show any remarkable change since 1959 to 1963, but increased to 2.35% and 4.26% in '64 and '65. These patients with both diseases increased between age of 30 to 60 years old, on the other hand the age peak of pulmonary tuberculosis was between age of 50 to 60 ?years old. Therefore we cannot decide that patients with both diseases recently increased following the increase of the old aged pulmonary tuberculous patients.
The numbers of patients suffering from both diseases at the same time (B group) increased markedly in '64 and '65 compaired with that of the previous 5 years, therefore the numbers of B group were equal to that of C group (suffering from pulmonary tuberculosis before the development of diabetes).
Before administration into our sanatorium a majority of A group (suffering from diabetes before pulmonary tuberculosis) had no insulin therapy. In B group a greater parts of patients administered into our hospital soon after the diagnosis of both diseases. In C group a majority of patients diagnosed as diabetes on administrated period and on the screening test of glycosuria 2 hours after breakfast. 28 hospitarized patients suffering from both diseases in '64 and '65 were classified into 20 adult type diabetics and 8 juvenile type diabetics. The rate of juvenile type diabetics in pulmonary tuberculosis were more than that of diabetics without pulmonay tuberculosis.
Fifteen cases had been observed more than a year after classified into two groups, fair controlled and uncontrolled ones, and we compaired their chest roentgenogram and tuberculaus bacilli in sputum. A greater parts of chest roentgenograms in fair controlled group improved moderately, but in uncontrolled group there were no improvement. Tuberculous bacilli in sputum in uncontrolled group also diminished in all cases. Having examined these growing worse cases, we consider that they were aggravated with hypoglycemia due to overdoses of insulin rather than deficient insulin therapy.
Accorping to our preliminary report in July, 1964, 41 out of 476 pulmonary tuberculous patients had positive urine glucose 2 hours after breakfast. 2 years after 46% of 435 patient without glycosuria are still hospitalized and 9.8% of them were dead. The other hand 51.2% of 41 cases with glycosuria are still in hospital and 12 % of them were dead.
Among 12 suspected diabetics 2 cases changed to diabetics 2 years later, 4 cases were suspected diabetics, but did not revealed normal pattern.
