Abstract
This report is a part of results in joint research carried out at Kyushu National Sanatorium. The apparent diabetes mellitus and the cases presented glycosuria were classified in four groups; A-group: under 110mg % of fasting blood sugar without diabetic therapy, B-group: below 140mg %, C-group: 140mg % to 200mg %, D-group: over 200mg % with diabetic therapy.
1) Cavities were seen radiologically in 70 % except D-group which had higher rate.
2) Improvement rate of tuberculoss lesions were 40% in A-group, 34% in B-group, 11% in C-group and 29% in D-group.
Aggravation rate of lesions were 4% in A-group, 5% in B-group, 11% in C-group and 29% in D-group. Improvement rate of cavities were 35% in A-group, 19% in B-group, 0% in C-group and 17% in D-group. Aggravation rate of cavities were 1% in A-group, 5% in B-group, 10% in C-group and 17% in D-group. Above percentage points out unfavorable progress of pulmonary tuberculosis with diabetes.
3) A.F.B. positive rate was 70% in the cases with cavities, in which only D-group had higher bacilli positive rate, but in the cases without cavity bacilli positive rate were 18% in A-group, 30% in B-group, 71% in C-group and 100% in A-group.
4) Negative conversion rate was 60% in the cases with cavity and 70% without cavity. Only D-group had lowere negative conversion rate.
5) In the cases with high fasting blood sugar level drug resistance appeared at an early stage and showed high rate.
Above results point out that control of diabetes mellitus is necessary for the treatment of tuberculosis, and in the cases which is difficult to control diabetes the device of chemotherapy is important by checking appearance of drug resistant A. F. B.
