Abstract
The increase of respiratory-tract infection with Pseudomonas aeroginosa have been recently observed.
We have studied the effect of Kasugamycin (KSM) on respiratory-tract infection with pseudomonas aeruginosa.
The cases were 2 cases of secondary infection with cavity drainage, secondary infection after cavernostomy, secondary infection after lobectomy, mixed infection of bronchial fistula, empyema, chronic bronchitis, bronchectasis, pulmonary abscess with pseudomonas aeruginosa.
1. The effect of Kasugamycin (KSM) I. M. (1g/day for 10 days.)
Result; effective 1 case. None effective 5 cases.
Side effect; all cases complained of local pain for injection, anorexia, and 1 cases showed increase of blood urea nitrogen.
2. The effect of local injection by 12.5%-5% KSM solution
Result; 5 cases became negative for Pseudomonas and 1 case showed decreased number. The effect was splendid.
Side effect; 1 case showed laryngitis
3. The effect of inhalation of 2.5%-2% KSM solution
Result; 2 cases became negative for pseudomonas but 1 case was not effected, Side effect; 2 cases complained of hoarseness.
