Abstract
For the purpose of detecting the immune anomaly, serum R. A. test (R. A. T.) was carried out on the inpatients during past 3 years.
1) The positive incidence of R. A. T. was 15.1%, 63 out of 418, thereof in liver disease highest 32.1%, 34 out of 106 in blood disease next 29.2%, 14 out of 48, in others 5.7%, 15 out of 264.
2) As contrast, the positive incidence in subjects received health examination was 13 out of 367, 3.5%.
3) In liver diseases, the positive incidence was in the following order: in cirrhosis 16 out of 33, 48.5%, in cancer 7 out of 21, 33.3%, in chronic hepatitis 9 out of 32, 28.1%, in acute hepatitis, 2 out of 20, 10.0%.
It was noted that with the perpetuation of hepatitis, the positive incidence became higher.
4) In blood diseases, the positive incidence was in Banti synndrome 8 out of 11, in idiopathic thrombopenic purpura 2 out of 6, in aplastic anemia 2 out of 7, in malignant lymphoma and acute myelogenous leukemia, 1 out of 6 and 11 respectively, and in multiple myeloma 0 out of 4.
For the occurence of R. A. factor in blood diseases, especially in Banti syndrome, the gammaglobulin anomaly due to chronic active process in liver as in observed in liver diseases may be responsible, however, the autoimmune process which is specific for each disease or case must be considerd.
