Abstract
Small outbreak of pharyngeal fever occured in Children's rooms in National Hospital of Sendai, November 1965, All patients were less than 8 year-old. Adenovirus type 3 was isolated from the throat swabs of the 6 cases with this disease of 10 and significant rise of HI antibody against adenovirus type 3 in paired sera obtained from the patients was demonstrated in 8 cases of 11. Then it was evident that the outbreak of pharyngeal fever was due to adenovirus type 3. Antibody against adenovirus type 3 in sera obtained from the children in the same rooms who did not suffer from the disease was also titrated. Neutralizing antibody was found in 22 cases (81.5%) of 27, although HI antibody was positive in 7 cases (25.9%) of 27. Thus it is suggested that most of susceptible children against adenovirus type 3 were infected with this virus and apparently suffered from the pharyngeal fever.
