Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Clinical Observation of Long Term Administration of Xlital
Akira YOKOTASaburo YOSHITAKEHiroo SHINAGAWA
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1968 Volume 22 Issue 4 Pages 424-430

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Abstract
Nineteen cases including four normal persons, seven diabetic patients and eight other patients were studied on the effect of long term administration of xylitol.
Thirty gram of xylitol were given orally daily to these cases for one month to thirteen months. Meanwhile the serum albumin, total cholesterol, the number of erythrocytes and hemoglobin content were measured periodically.
The cases with anemia and hypoproteinemia recovered after one or two months administration of xylitol. The cases which showed nomal value of serum albumin, normal number of erythrocytes and normal hemoglobin contents fluctuated within normal ranges during the long term administration of xylitol for three to thirteen months.
The effect of xylitol to the total cholesterol is hard to be discussed by this time.
Thus the long term administration of xylitol would not make unfavorable results, but would smoothen the carbohydrate metabolism by accelerating the Warburg-Pickens circle, and wield good influences to the correlated metabolism.
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© Japanese Society of National Medical Services
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