Abstract
A Case of periodic paralysis presented clinically interesting course.
1) High carbohydrate diet produced paralysis, in which second degree A-V block of Wenckebach type and hypokalemic type EKG was seen, and recovered by Thiamine monophosphate disulfide (TMPDS) 100mg I. V.
2) Despite of the previous administration of O. Butyryl thiamine disulfide (BUTDS) 150mg P. O., the paralysis with hypokalemia and A-V block of Wenckebach type was provocated by I. V. drip infusion of 50% glucose 400ml.
Regular insulin 30 units I. M. made the palsy more severe with lowering of serum potassium, although administration of insulin improved the second degree A-V block of Wenckebach which was already noted just before the injection as the first degree A-V block with prolonged PQ and flat T.
Although no recovery of the palsy was obtained by an administration of Potassium chloride 5 gm. P. O., the alteration of hypokalemic type EKG was noted with the more elevated T and the disapperance of U wave.
TMPDS 100mg I. V. followed to Potassium chloride 5gm, induced complete recovery.
3) Previous administration of Potassium salts of aspartic acide 3 to 6gm, and BUTDS 150 to 300mg P. O. prevented paralysis followed by the I. V. drip infusion of 50% glucose
400 ml or the high carbohydrate diet.
