Abstract
Percutaneous transhepatic cholangiographies were carried out 35 times on 30 cases, in which cholangiographies were obtained 24 times on 20 cases, at the 2nd Tokyo National Hospital from June, 1967 up to September, 1968. This report is the result of comparative study of each contrast medium, i. e.: Conray, Conraxin L, Urograf in, Urovison and Biligrafin. The former four consist of sodium salt, methylglucamine salt of their mixture of various derivatives of triiodobenzoic acid, which has 3 iodines in a molecule, and the latter one, methylglucamine salt of adipin-diamino-triiodobenzoic acid, which has 6 icdir.es in a molecule.
Basic experiments were aimed to compare easiness of mixing with bile, clearness of radiolucency in interposition of biliary stones and ability of making contrast in narrow tube by these contrast media. Clinically, the following points were studied in practical FTC examinations; the clearness of contrast in intrahepatic ducts, radiolucency in a case of biliary stone, presence of fluid level between contrast medium and bile, the side effect and so on.
The result suggested that Biligrafin was better to distinguish in a case of biliary stone and the others were more excellent to find out abnormalities of intrahepatic ducts and common duct. All of them were not satisfactory in mixibility with bile. Any troublesome side effect did not occur in each contrast medium.