Abstract
The changes in blood pH, Pco2, plasma bicarbonate and the electrcencephalogram were evaluated in 67 studies of 35 patients with uremia due to acute and chronic renal failure.
The pattern of the electroencephalogram frequencies has been quantated by the method of Kiley and Hines, all of whom were studied by serial electroencephalogram.
As uremia became worse, the electroencephalogram became abnormally slow. When uremia was relieved by recovery of renal function or by effective therapy, the electroen-cephalogram returned toward normal, but blood chemical leveles, blood pH, Pco2 and plasma bicarbonate did not run parallel with. Our experiences suggest that the presence of slow activity less than 7 cps in 30 per cent of the electroencephalogram indicates need for peritoneal or hemodialysis.
