Abstract
Two cases of pinealoma are reported.
Case 1. A 27 aged Japanese male, who had been treated for diabetes insipidus for 2 years. At about 10 months prior to death he complained of dizziness, dysarthria and dysbasia. He died with severe dysphagia, as a sign of bulbar palsy.
An about 20×20mm. sized tumor was found in the hypothalamic region, which was extended to the entire ventricular walls. The tumor cells infiltrated to the posterior lobe of the pituitary gland and widely into the subarachnoid space. Detailed examination revealed neoplastic growth of pineal body.
Case 2. A 24 aged Japanese male, who had complained anorexia, emaciation, nausea, vomiting and autism for about 11 months, later he was diagnosed as schizophrenia. He died with frequent vomiting and coma lasted for several days. An about 30×20mm. sized tumor was found in the hypothalamic region extended to pituitary gland downward, to the IIIrd and lateral ventricular walls upward and into subarachnoid space. Detailed examination revealed neoplastic growth of pineal body.
These 2 cases were histologically diagnosed pinealoma, which showed typical mosaic structure; larger cell group separated by smaller dark cell zone. The histological pictures of these 2 cases to be appropriated to “germinoma” by Friedman or “atypical teratoma” by Russel.
