Abstract
It has been previously described that the immunoglobulin G (Ig G) was elevated about 20 to 30% higher in aged than that of youth. In Kure National Hospital, we examined Ig G of 292 blood samples from 139 subjects, who were given diagnoses of SMON but had not any evidences to have diagnosis of hepatitis or tuberculosis.
It has been resulted from our data that increase of Ig G was obviously observed in SMON, even though the diagnosis of SMON was given in relatively aged group in both male and female.
Authors also have some evidences that immunoglobulin M (Ig M) was elevated in the relatively acute stage of about 30% of SMON, particularly during the first 3 months after onset, as A. Kosara et al, already reported. Furthermore, in the present study, there are slight increase of serum GOT and GPT activities in many who were diagnosed as SMON.
Recently, it has been discussed whether SMON would be caused by viral infection or quinoform intoxication, but the exact cause of this disease is still unknown at present time.
In the near future, we will study whether Ig G may be elevated by some factor which increase serum GOT and GPT.
