Abstract
In surgical area the antibiotics have been usually given to patients after operation to prevent the postoperative infection. In the present study, the relationship between the antibiotics prophylactically given after operation and the etiological organisms of postoperative infection was analyzed to re-evaluate the significance of the prophylactic use of antibiotics after operation.
Postoperative tracheobronchitis and pneumonia were caused by Str. viridans, Neisseria and Str. anhemolytics, and the majority of wound infections by E. coil, Klebsiella, Enterococcus and Staphylococcus aureus. Biliary tract was infected by E. coil and Enterococcus, and urinary tract by E. coil, Klebsiella and Pseudomonas aeruginosa. All of the etiological organisms of postoperative infections were resident flora. In addition, the organisms were resistant against the antibiotics given after operation. Thus, the antibiotics given to the patients after operation might not prevent postoperative infection but might select the resistant organisms from resident flora.
Therefore the practical use of antibiotics after operation should be reconsidered. It is more important to made an effort for early diagnosis of postoperative infection and for immediate use of the most efficient antibiotics.
