Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Studies on the Hemolysis caused by Various Injections
Mihoko YOSHIDAKuniko EMOTOHiroko IIJIMAEtsuko WATANABEShiro YAMAGUCHITakao GOTO
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JOURNAL FREE ACCESS

1976 Volume 30 Issue 2 Pages 160-165

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Abstract
As the hemolysis by injection is important, especially in regard to the contracture of quadriceps femoris muscles, we tested the hemolysis in vitro by 116 injections for intra-muscular used in our hospital. In addition we tested the osmotic pressure and pH. The following results were obtained,
(1) The rate of injections showed hemolysis was 58%, 42% of it discolored and 27% of all showed complete hemolysis.
(2) We observed hemolysis over 4000 m. o. s. or below 120 m. o. s., but we observed many injections showed complete hemolysis or in part even in near the physiological osmotic pressure.
(3) There were hemolysis and discolor below pH 3.0 or over pH 8.0, but many in-jections did even in neutral,
(4) We were unable to clear the relation between hemolysis and the chemical structures of intramuscular injection, but we have found some injections showed hemolysis in vitro related hemolytic anemia and contracture of quadriceps femoris muscle.
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© Japanese Society of National Medical Services
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