Abstract
A new method of charcoal seroperfusion using IBM 2997 blood cell separator combined with DHP-1, which is the activated charcoal-filled tube, was developed by us and was applied to a patient with paraquat poisoning.
The patient was 33-year-old female, who took paraquat (glamoxan) for suicide. Charcoal seroperfusion was done three times over 3 days showiug concentrations of urinary paraquat decreased remarkably.
Charcoal seroperfusion is the method which can separate blood into blood cell components and serum by centrifugation and only the serum canbe passed through charcoal to adsorb the poisoning substance. This method is considered to be safer and more effective compared to the conventional hemoperfusion method, because there is no adsorption or destruction of blood cell to charcoal.
This patient died of acute circulatory failure following heart attack. Autopsy findings revealed interstitial myositis of the heart characteristic of paraquat poisoning. The histological findings of the lung, liver and kidneys were also described in detail.
