Abstract
We report a 5-years-old boy with hypohidrotic ectodermal dysplasia, He was sensitive to hot environments and had frequent episodes of body temperature elevation, especially in summer. The family history was negative for hypohidrotic ectodermal dysplasia. The sweat gland distribution test showed that his sweat glands guantitative defect and patchy anhidrosis. His sweat glands response to acethylcholine was lowered than the control.
A biopsy from the sole, which responded to the sweating test, showed that sweat glands were present but they were decreased in number. We think that some genetic and environmental factors affected his ectodermal organs in the embryonic stage, and resulted in his abnormal sweat glands
