Abstract
We report a case presumably thought to be in early stage of membranoproliferative glomerulonephritis.
A 19-year-old male was admitted to our hospital with a chief complaint of chance proteinuria. Since persistent hypocomplementemia was noticed, renal biopsy was performed, which revealed segmental membranoproliferative lesions in three out of eleven glomeruli. Immunofluorescence also revealed focal segmental deposition of IgG, IgM, β1C and C1q along the capillary walls with granular pattern. Intramembranous and messangial electron dense deposits and numerous virus-like particles were recognized by electron microscopic study.
Those findings resembld to that of lupus nephritis, however clinical findings did not fulfill the criteria proposed by American Rheumatoid Association.
Steroid was effective to this patient and urinary protein decreased. Focal segmental membranoproliferative glomerulonephritis may be an early stage and/or a mild form of idio-pathic (diffuse) membranoproliferative glomerulonephritis
