Abstract
A case of 59-year-old male of primary malignant fibrous histiocytoma of the lung is reported. Primary malignant fibrous histiocytoma of the lung is rare, and commonly seen in deep fascia, skeletal muscles of the extremities, mediastinum and in the peritoneum.
The tumor was predominantly fibroblastic, had a characteristic story-form pattern, and consisted of large histiocytes with bizarre nuclei and a vacuolated cytoplasm.
The patient complained of cough, sputum and slight dyspnea. Chest X-ray revealed a mass shadow with atelectasis in the right lower lung field. The right middle and lower lobes were resected. Histologic examination showed features of malignant fibrous histiocytoma, peribronchial lymph nodes were free of disease. Although the patient was treated with chemotherapy postoperatively, he died from massive bleeding due to rupture of metastatic brain tumor about eight months after operation.
This case appears to be the first reported primary malignant fibrous histiocytoma of the lung in Japan and only five cases have been reported in the world literature.
