Abstract
A case of male child with tumor formation in the pancreatic head and hepatic hilus asso-ciated with persistent mosquito hypersensitivity was reported. The patient has suffered from severe systemic reaction by mosquito bite since 2 years of age and developed lympho-reticular proliferation at the age of 10. He finally developed acute pancreatic necrosis. It was considered that this tumor showed the figure of rapidly growing fatal reticulosis, and that the histological findings demonstrated histiocytic medullary reticulosis with tumorous transformation. These findings might suggest the close correlation between basic mosquito allergy and tumor formation.