Abstract
A 7-year-old girl first noticed slight difficulty in gait and pes equinovarus. Later the symptoms gradually worsened. Neurological examination revealed spastic gait, exagger ated deep tendon reflexes, pes equinovarus, rigidity, postural and action tremor of upper limbs. In the morning the neurological examination was normal. In the afternoon she had a tendency to fall. CT-scan showed mild frontal lobe atrophy. Because of clinical features, L-DOPA therapy was started. L-DOPA produced a dramatic improvement of symptoms. Although HPD might reflect the functional disturbance of the striatum, CT-findings suggested that the pathogenesis of HPD might be linked with frontal lobe atrophy
