Abstract
It is believed that immunological competence of cellular and humoral immunity declines by aging. This is because the histological changes and atrophy of the various organs of the body, involution of thymus and resultant hypofunction of T-cells and abnormality of the immunoglobulin from the group of B-cells lead to the onset of the diseases in the elderly people.
In the present paper, the pathology of the immunodeficiency occurring in the aged is described, with detailed description of senile pneumonia, megaloblastic anemia, multiple myeloma, leukemia and other autoimmune diseases, all of which are common in the general clinics for the elderly patients.