Abstract
We measured the serum total cholesterol (T-C), high density lipoprotein cholesterol (HDL-C), low density lipoprotein (LDL), very low density lipoprotein (VLDL) by enzyme method (T-C), precipitate method (HDL-C) and BLF reagents (LDL, VLDL from Eiken), and the following results were obtained.
1) The serum T-C, HDL-C, LDL and VLDL in normal controls (male 20, female 20) were 167.3±35.1 mg/dl, 54.1±13.8 mg/dl, 319±72.3 mg /dl, 106±52.8 mg/dl for male indivi-duals; 169.3±24.7 mg/dl, 58.9±13.3 mg, /dl, 330±62.3 mg/dl, 113±38.1 mg/dl for female indi-viduals, respectively.
2) The serum T-C, HDL-C, LDL and VLDL of PMD were 158.9±36.4 mg/dl, 36-4±8.8 mg/dl, 334.6±91.6 mg/dl, 130.4±107.6 mg/dl for male patients with Duchenne type PMD, 107.2±40.2 mg/dl, 40.2±8.9 mg/dl, 316.9±103.9 mg/dl, 170.4±101.3 mg/dl for male patients with LG type PMD;194.7±55.9 mg/dl, 41.5±16.4 mg/dl, 364.3±75.4 mg/dl, 171.9±224.2 mg/dl for male patients with other diseases; 189±64.3 mg/dl, 43.8±9.9 mg/dl, 436.5±138.4 mg/dl, 96.2±38.1 mg/dl for female patients with LG type PMD;230±33.9 mg/dl, 41.5±7.4 mg/dl, 498.8±111.3 mg/dl, 271.3±210.3 mg/dl for female patients with FSH type PMD;180.4±49.5 mg/dl, 49.0±19.2 mg/dl, 361.4±157.6 mg/dl, 102.3±56.6 mg/dl for female patients with other diseases.
The HDL-C and % HDL-C (HDL-C/T-C) were low in the patients with PMD (espe-cially obese patients). It has been described that low HDL-C level is related to the de-velopment of arteriosclerosis, so we have to carefully observe serum T-C, HDL-C, LDL and VLDL levels in patients with PMD at regular intervals.
