Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Anesthesia for Patients with Hepatic Dysfunction
Mitsuru YAMADA
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Keywords: GOE
JOURNAL FREE ACCESS

1987 Volume 41 Issue 1 Pages 15-19

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Abstract
The effects of several different general anesthetics on routine liver function tests were evaluated in patients with abnormal liver function. A total of 128 cases of general anesthesia were divided into six groups, i, e., control, modified NLA, original NLA, GOE, Ketamin micro mini-drip method, and a group receiving blood transfusions.
A total of thirteen parameters including GOT, GPT, γ-GPT, LDH, ALP, LAP, ChE, TTT, ZTT, total cholesterol, cholesterol-ester ratio and T. P, were evaluated before, during, immediately after, 24 hours after and one week after surgery.
The adverse effects on liver function by various types of anesthesia can be summarized as follows: Ketamin micro mini-drip>original NLA>modified NLA>GOE where Ketamin micro mini-drip had the most adverse effect and GOE the least.
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