Abstract
From 1974 to 1985, 19 patients (10 families) with familial adenomatosis coli (FAC) were treated at Osaka National Hospital. At the time of initial diagnosis, 7/9 (78%) of the untreated patients with FAC already had cancer, but only 1/10(10%) of their relatives with FAC had cancer.
Ten patients not developing rectal cancer underwent subtotal colectomy and ileorectal anastomosis at a higher level. In these patients bowel movement was normal. But 2 patients without a careful follow-up developed cancer in the remained rectum.
