Abstract
Serum theophylline (THP) concentration of 2 and 6 hours after oral administration of sustained-release preparation of THP during R. T. C. therapy were compared. The mean age of patients (N=20) was 64.8 years (S. D.=8.31) and the mean weight was 50.0kg (S. D.=9.07). The serum THP concentration was measured by T. D. X. method.
The following results were obtained: The regression equation of 2 (X) and 6 hours (Y) was indicated by Y=1.17X+0.42, and the coefficient of correlation was 0.968. The ratio of 6 and 2 hours was about 1.23 and the S. D, was 0.14.
