Abstract
During the 10-year period, 1976—1985, a total of 8741 women were delivered at Sendai National Hospital and 56 women (0.64%) of them were diabetic pregnant patients. The clinical outcome of 56 diabetic patients was analyzed.
The incidence of diabetic patients increased about three-fold from 0.43% to 1.17%. Mean maternal age for diabetic patients (31.2±4.1 years) was significantly older than normal preg-nant women (28.5±3.8 years). Over 19 per cent of the diabetic patients were 30 years of age or greater and nullipara. According to the classification of White, 27 of the 56 cases were in GDM, 12 in class A, 11 in B, 2 in C and 4 in D. Twenty-five per cent of the patients were treated with insulin. Forty-nine per cent of diabetic patients had at least 1 diabetic relative. The patients with toxemia were found in 33.9% and hydroamnion in 3.6%. Cesarean section was performed in 43.80 of diabetic patients. The duration of gestation at the moment of delivery was 39.4 weeks in GDM and progressively less in classes A through D according to the severity of the diabetic disorders. There was significant difference in the mean birth weight of diabetic patients and no diabetic patients (3550 g versus 3140 g). There were 14 infants (24.6%) who weighed 400 g or more. The perinatal mortality was 3.50. Infant morbidity was demonstrated by the following percentages: hyperbilirubinemia requiring treatment, 10.5%; hypoglycemia, 8.8%; respiratory distress syndrome, 3.5%; and hypogalcemia, 1.8%. One infant had congenital anomaly of external auricle.