Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
A Natural History in Patients with Duchenne Muscular Dystrophy(DMD)
Shizuro NAKAMICHIYoshimi AKIMOTOKatsuro IGARASHITadayuki KURONUIMANobuo KOIDESusumu OTAKEShunsuke NARITA
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Keywords: DMD
JOURNAL FREE ACCESS

1988 Volume 42 Issue 8 Pages 751-754

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Abstract
We present 3 cases of DMD. The disease developed at their infant period in all 3 cases. They were admitted at 4-9 years old. They fell in stage V at 9-10 years old. The height and body weight were small compared with normal children. Vital capacity had been progressively decreased to 610±25 cc at their terminal stages and tracheotomy was done in 2 cases.
CPK, LDH, Aldolase, GOT, GPT showed high values in the beginning of the disease, and they decreased gradually with the progression of the disease. PaO2, PaCO2 demonstrated abnormal values and the patients fell into a delirious state. The serum pH showed respiratory acidosis.
We used several methods including postural drainage, vibrator and, tapping in order to discharge sputum. All of these 3 cases died of respiratory insufficiency, pneumonia and bleeding from tracheo-arterial fistula, respectively.
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© Japanese Society of National Medical Services
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