Abstract
We studied 30 cases of intrauterine growth, retardation (IUGR) children 0-3, years of age, born in this hospital at the 28th week or later with birth weights of less than 2500 grams from mothers with toxemia during the period from January 1, 1984 to December 1988. Also, 103 cases of IUGR children 0-3 years of age, born at 28 weeks or later with birth weights of less than 2500 grams from non-toxemic mothers in 1984, 1985 and 1987 were studied. Development quotients were evaluated using the Tsumori questionnaire-type mental development test.
Among the toxemic IUGR's, one case of cerebral palsy was observed. In the non-toxemic IUGR's, two cases of cerebral type paralysis and two cases of mental developmental retardation were observed. These abnormalities were 2.7896 of the toxemic group and 3.88% of the non-toxemic group.
The cause of all three cases of cerebral paralysis was thought to be hypoxic ischemic encephalopathy, which was diagnosed in two cases after fetal monitoring detected fetal asphyxia neonatorum. In the third case, however, fetal monitoring did not detect asphyxia neonatorum due to the absence of Wharton's jelly in a 10-centimeter portion of the umbilical cord.
In the two diagnosed cases of fetal non-asphyxia neonatorum, mental development retardation appeared with complications of neuroblastoma in one case and hemilateral maniphalanx rigidity in the other. The causes, however, are still unknown.