Abstract
A case of malignant Brenner tumor (stage c) is presented. A 57-year-old woman visited our hospital complaining of lower abdominal mass. As malignant ovarian tumor was suspected on pelvic and ultrasonic examination, abdominal total hysterectomy with salpingo-oophorectomy and partial omentectomy were performed. The child head-sized tumor originated from the left ovary and the cut surface showed the mixed pattern with solid and cystic component. Microscopically, the tumor was composed of nests of transitional and squamous-appearing epitherial cells which showed atypia with 3-4 mitoses per 10 high power field and stromal invasion. The stroma consisted of fibrous connective tissue. The component of benign Brenner tumor was not found. There were no malignancies in the urinary tract. On these pathological findings, a diagnosis of malignant Brenner tumor was made. After operation, combined chemotherapy of cisplatinum, vinblastin and bleomycin were perfomed. Follow-up laparoscopy after 16 months revealed no recurrence.
