Abstract
A 62-year-old housewife lost consciousness on March 6 1985. She was admitted to the emergency clinic of our hospital because of disturbances of consciousness. On March 10, she developed anogenital and facial skin rash and she was referred to us on March 15. Herpes simplex virus (HSV) infection was suspected. Anti-viral agent, Ara A was administered for 8 days. Skin rash became dry with an elevation of HSV-CF antibody titre from 16× to 64× in 4 weeks, which confirmed the diagnosis of HSV infection, although recovery of her conscionsness impairment was delayed and partial.