Abstract
Approximately 6% of dialysis cases of patients under 18 years of age in Japan, resulted from Henoch-Schönlein purpura nephritis. We conducted a research on cases of Henoch-Schönlein purpura nephritis, from 15 medical centers, with a total of 92 patients, mean age at onset 8.0±2.7 (years).
The prognosis was classified into the following groups;
1st group-cured, 2nd group-improved,
3rd group-unchanged, 4th group-worse.
71.6% of the patients belonged to the 1st and 2nd groups, with a favorable prognosis. 6.5% including 3.2% dialysed patients, had a poor prognosis.
With respect to the degree of hematuria, proteinuria and prognosis there was no recognized correlation in each group. The findings of renal biopsy indicated a favorable prognosis in II of the ISKDC (International Study of Kidney Disease in Children) classification.
On the other hand, cases with a poor prognosis were distributed in 111 a of the above classification.
No significant difference was recognized for prognosis by use or non-use of steroids.
At present repeated biopsy as well as clinical findings is considered to be important, for determination of long-term prognosis of purpura nephritis.
