Abstract
Clinical study of HCV related hepatocellular carcinoma was carried out with reference to the prognosis to assure the hypothesis that the patients with HCV related hepatocellular carcinoma might have better prognosis compared with the prognosis of another hepatocellular carcinoma, especially with HBV related hepatocellular carcinoma. Meanage of the patients with HCV related hepatocellular carcinoma was significantly older than those with HBV related hepatocellular carcinoma at the time when hepatocellular carcinoma was diagnosed. Among the patients classified as Child-pugh B, there was a higher number of patients receiving surgical resection, TAE and TAI in HCV related hepatocellular carcinoma than another hepatocellular carcinoma, although no significant difference was found between the stages of underlying chronic liver diseases assessed by Child-pugh classification independent of causal agent of hepatocellular careinoma. Moreover, the both positive ratio of AFP and PIVKA II was higher in patients with HBV related hepatocellular carcinoma compared with HCV related hepatocellular carcinoma. These findings suggest that the number of patients with HCV related hepatocellular carcinoma receiving surgical resection, TAE and TAI is increased significantly compared with HBV related hepatocellular carcinoma as a result from the reciprocal effects of these factors, so that the patients with HCV related hepatocellular carcinoma might have longer survival.
